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Healthcare providers should assess heart rate and blood pressure both at the start of treatment and throughout its course, especially for patients with arrhythmias or heart failure

Studies have found the chemokines levels, such as CXCL13, CXCL9 and CCL2, are significantly increased in MS (115, 116), potentially activating the p38 mitogen-activated protein kinase (MAPK) pathway and compromising the BBB (117)

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More importantly, tight blood glucose control is essential during pregnancy, and the effects of GLP-1 drugs on blood sugar regulation can vary, potentially increasing the risk of hypoglycemia